Antifibrotic effect of < em > Pluchea sagitallis < /em > (Lam.) cabrera aqueous extract in grx cell lineage

In conclusion, theP. sagittalis aqueous extract reduces the growth and proliferation of GRX cells and induces the reversal of activated towards a quiescent phenotype. There was no decrease in cell proliferation either by necrosis or by apoptosis via activation of the senescence. Thus, our data suggest that the extract showed an antifibrotic effect, possibly by activating phenotype reversal.
Source: International Journal of Phytomedicine - Category: Science Authors: Source Type: research