In vitro antioxidant anti inflammatory and cytotoxicity activities from Hexane extract of < em > Bryonopsis laciniosa < /em > fruits.

Bryonopsis laciniosaalso known as “Shivlingi” annual climber with bright red fruits and is reported to be highly medicinal in India.As a folk medicine, the plant is used in treatment of broad range of diseases and disorders. In the present study, Hexane extract ofB. laciniosafruits were used to evaluateinvitro anti inflammatory, antioxidant and Cytotoxicity (towards MCF-7 cell line) activities. In vitro anti inflammatory activity by inhibition of protein denaturation, antioxidant assays like DPPH, ABTS, H2O2 and FRAP were used to measure the antioxidant capacity of the hexane extracts and cytotoxicity activity using MCF-7 breast cancer cell line. Hexane extract showed the effective antioxidant activity in all assays compared to ascorbic acid and BHT. The results for In vitro anti inflammatory activity of hexane extract and Dichlofenac drug were equivalent, hexane extract showed promising activity for inhibition of protein denaturation assay. The cytotoxicity activity from hexane extract was noticeable against MCF-7 cell line. The overall results show potential application ofBryonopsis laciniosafruits suggesting their potential application as a health-promoting functional ingredient or natural preservative in foods.
Source: International Journal of Phytomedicine - Category: Science Authors: Source Type: research