Long non-coding RNA CHRF facilitates cardiac hypertrophy through regulating Akt3 via miR-93

Non-coding RNAs, including long non-coding RNAs (lncRNAs) and microRNAs (miRNAs), have been demonstrated as central mediators in cardiac hypertrophy responses. LncRNA cardiac hypertrophy related factor (CHRF) has been reported to be implicated in cardiac hypertrophy. However, the underlying mechanisms of CHRF have not been thoroughly elucidated.

Source: Cardiovascular Pathology - April 11, 2018 Category: Cardiology Authors: Yang Wo, Jie Guo, Peihui Li, Hongxia Yang, Jinshan Wo Tags: Original Article Source Type: research