Comparing coronary artery fibromuscular dysplasia with coronary atherosclerosis: from clinical to histopathological characteristics

Fibromuscular dysplasia(FMD) is a non-inflammatory and non-atherosclerotic disease that leads to aneurysm, dissection, and vascular occlusion. FMD is commonly involved with renal artery (most commonly) and internal carotid artery, while the vertebral artery, iliac artery, subclavian artery, and visceral artery are seldom involved. Patients with FMD are usually young women [1]. Although the first case was reported 75years ago, the knowledge of FMD remains insufficient [2]. Genetic factors have been found associated with this disease, for example, the phosphatase and actin regulator 1 (PHACTR1) is related to FMD in some families [3,4].
Source: Cardiovascular Pathology - Category: Cardiology Authors: Source Type: research