N-acetylcysteine Protects Against Chorioretinal Damage Induced by Photodynamic Therapy for Experimental Choroidal Neovascularization in a Rat Model

Photodynamic therapy (PDT) with verteporfin is a partially selective vaso-occlusive treatment targeting chorioretinal abnormalities. PDT was initially used to treat certain types of neovascular age-related macular degeneration (AMD). PDT employing verteporfin as a photosensitizer preferentially occludes choroidal neovascularization (CNV) with minimal damage to collateral structures such as the retinal pigment epithelium (RPE) and neural retina [1,2], and it suppresses CNV leakage in patients with neovascular AMD [3 –7].
Source: Photodiagnosis and Photodynamic Therapy - Category: Laser Surgery Authors: Source Type: research