Catalase A is involved in the response to photooxidative stress in Pseudomonas aeruginosa

Visible light, either alone or in combination with dyes, is a potential tool for controlling bacterial pathogen growth [1,2]. Antimicrobial Photodynamic Therapy (aPDT) is an approach that combines the use of an exogenous dye (photosensitizer, PS) and visible light, in an aerobic atmosphere, to induce photooxidative stress in bacteria. The irradiation of PSs with visible light causes singlet oxygen (1O2) and/or ROS (H2O2, OH, O2) to arise, thereby lethally damaging bacterial cell envelopes and/or cytoplasmic macromolecules [3].

Source: Photodiagnosis and Photodynamic Therapy - April 27, 2018 Category: Laser Surgery Authors: Viviana Teresa Orlandi, Eleonora Martegani, Fabrizio Bolognese Source Type: research