Personalized Computational Modeling of Left Atrial Geometry and Transmural Myofiber Architecture

Atrial fibrillation (AF) is a supraventricular tachyarrhythmia characterized by uncoordinated atrial activation with consequent deterioration of mechanical function. Affecting an estimated 33 million people worldwide (Rahman et  al., 2014), AF is the most common arrhythmia and associated with an increased long-term risk of other cardiovascular diseases. Personalized computational modeling provides a novel framework for integrating and interpreting the role of electrophysiology (EP) in the development and progression of AF (Trayanova, 2014; Trayanova and Chang, 2016).

Source: Medical Image Analysis - April 5, 2018 Category: Radiology Authors: Thomas E Fastl, Catalina Tobon-Gomez, Andrew Crozier, John Whitaker, Ronak Rajani, Karen P McCarthy, Damian Sanchez-Quintana, Siew Y Ho, Mark D O ’Neill, Gernot Plank, Martin J Bishop, Steven A Niederer Source Type: research