Bone turnover markers after the menopause: T-score approach

Bone turnover increases at the menopause and is associated with accelerated bone loss. However, it is not known to what extent there is an imbalance between the processes of bone resorption and bone formation, nor whether it is the rate of bone turnover or the bone balance that is most closely associated with the rate of bone loss.We studied 657 healthy women ages 20 to 79 from five European cities (the OPUS Study) and divided them into two premenopausal age groups, 20 to 29 (n=129), 30 to 39years (n=183), and three postmenopausal groups 1 to 10years (n=91), 11 to 20years (n=131) and 21+ years since menopause (n=123).

Source: Bone - March 15, 2018 Category: Orthopaedics Authors: Fatma Gossiel, Hibatallah Altaher, David M. Reid, Christian Roux, Dieter Felsenberg, Claus-C Gl üer, Richard Eastell Tags: Full Length Article Source Type: research