Exercise prevents high fat diet-induced bone loss, marrow adiposity and dysbiosis in male mice
High fat diets can have detrimental effects on the skeleton as well as cause intestinal dysbiosis. Exercise prevents high fat (HF) diet-induced obesity and also improves bone density and prevents the intestinal dysbiosis that promotes energy storage. Previous studies indicate a link between intestinal microbial balance and bone health. Therefore, we examined whether exercise could prevent HF-induced bone pathology in male mice and determined whether benefits correlate to changes in host intestinal microbiota.
Source: Bone - Category: Orthopaedics Authors: Laura R. McCabe, Regina Irwin, Arjun Tekalur, Christian Evans, Jonathan D. Schepper, Narayanan Parameswaran, Mae Ciancio Tags: Full Length Article Source Type: research
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