Kinase inhibitors: the road ahead

Nature Reviews Drug Discovery 17, 353 (2018). doi:10.1038/nrd.2018.21 Authors: Fleur M. Ferguson & Nathanael S. Gray Receptor tyrosine kinase signalling pathways have been successfully targeted to inhibit proliferation and angiogenesis for cancer therapy. However, kinase deregulation has been firmly demonstrated to play an essential role in virtually all major disease areas. Kinase inhibitor drug discovery programmes have recently broadened their focus
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Review Source Type: research