Multi-criteria optimization achieves superior normal tissue sparing in intensity-modulated radiation therapy for oropharyngeal cancer patients

Combined concomitant chemoradiotherapy is the standard treatment for non-resectable patients with oropharyngeal cancer (OPC), and is also preferable for resectable patients whose anticipated functional outcome with surgical treatment is poor [1]. Particularly, OPC with human papilloma viruses more sensitive to radiotherapy and chemotherapy [2 –4]. Studies demonstrated that intensity-modulated radiation therapy (IMRT) is associated with better locoregional control, survival rates, quality of life and less complication of radiotherapy for OPC [5–12].

Source: Oral Oncology - April 4, 2018 Category: Cancer & Oncology Authors: Jianghong Xiao, Yan Li, Huashan Shi, Tangel Chang, Yong Luo, Xuetao Wang, Yang He, Nianyong Chen Source Type: research