Prolonged linezolid use is associated with the development of linezolid-resistant Enterococcus faecium

We assessed risk factors for and outcomes of linezolid-resistant vancomycin-resistant Enterococcus faecium (LRVREF) bacteremia over 7 years. Thirty-four LRVREF cases were matched to 68 linezolid-susceptible VREF controls. The odds of bacteremia with LRVREF increased by 7% for each additional day of prior linezolid exposure.

Source: Diagnostic Microbiology and Infectious Disease - February 3, 2018 Category: Microbiology Authors: Tiffeny T. Smith, Pranita D. Tamma, Tiffany B. Do, Kathryn E. Dzintars, Yuan Zhao, Sara E. Cosgrove, Edina Avdic Source Type: research