Comparison of disk diffusion and agar dilution methods for gentamicin susceptibility testing of Neisseria gonorrhoeae

Gentamicin is a promising antibiotic for the treatment of multidrug-resistant gonorrhea. International guidelines do not list breakpoints for gentamicin. However, tentative susceptibility breakpoints for MIC and disk diffusion methods have been proposed. The aim of this study was to analyze the suitability and reliably of disk diffusion to monitor the susceptibility to gentamicin. We studied 237Neisseria gonorrhoeae isolates obtained in 2013 and 2015. The MIC and disk diffusion methods were performed according to CLSI guidelines.
Source: Diagnostic Microbiology and Infectious Disease - Category: Microbiology Authors: Source Type: research