Colistin susceptibility testing and Vitek-2 ™: is it really useless?

In this study we evaluated the performance of Vitek-2 ™ (bioMérieux, Marcy-L'Etoile, France) on determination of colistin susceptibility in comparison with gold standard broth microdilution method. The Vitek-2 showed 90.1% of essential agreement (EA) and 91.4% categorial agreement (CA), for Enterobacteriaceae isolates. In addition, 0.7% of major err ors (ME) and 7.94% of very major errors (VME) was observed. However, K. pneumoniae and E. coli, the Vitek-2 showed better performance for isolates with ≤0.5 or≥16μg/mL MICs.

Source: Diagnostic Microbiology and Infectious Disease - April 8, 2018 Category: Microbiology Authors: Raquel Girardello, Ana Paula Cury, Maria Renata Gomes Franco, Thais Romano Di Gi óia, João Nóbrega de Almeida, Maria Rita Elmor de Araújo, Alberto José da Silva Duarte, Flavia Rossi Source Type: research