Detection of urothelial carcinoma, upper tract urothelial carcinoma, bladder carcinoma, and urothelial carcinoma with gross hematuria using selected urine-DNA methylation biomarkers: A prospective, single-center study
Hematuria is the most common symptom of urothelial carcinomas (UC) but is often idiopathic. Cystoscopy is expensive which involves considerable patient discomfort, and conventional urine cytology for noninvasive UC detection and disease monitoring suffers from poor sensitivity. We aim to evaluate the performance of genes selected from a previous study in detecting UC, especially among patients with gross hematuria, as well as upper tract urothelial carcinoma (UTUC) and bladder carcinoma separately, in voided urine samples.
Source: Urologic Oncology: Seminars and Original Investigations - Category: Urology & Nephrology Authors: Run-Qi Guo, Geng-Yan Xiong, Kai-Wei Yang, Lei Zhang, Shi-Ming He, Yan-Qing Gong, Qun He, Xue-Ying Li, Zi-Cheng Wang, Zhen-Qing Bao, Xue-Song Li, Kai Zhang, Li-Qun Zhou Tags: Original article Source Type: research
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