Psychosis in a 22-Year-Old Woman With Narcolepsy After Restarting Sodium Oxybate

Narcolepsy is a chronic, often debilitating sleep disorder characterized by intense and excessive daytime sleepiness, hypnopompic and hypnagogic hallucinations, sleep paralysis, and cataplexy.1 Sodium oxybate, the sodium salt of γ-hydroxybutyrate (GHB), is an effective treatment for moderate-to-severe excessive daytime sleepiness and cataplexy associated with narcolepsy.2,3 The precise mechanism of sodium oxybate is unknown, but likely involves GABAB activation in addition to other pathways causing central nervous system ( CNS) depression.
Source: Psychosomatics - Category: Psychiatry & Psychology Authors: Tags: Case Report Source Type: research