Clozapine Discontinuation and Malignant Catatonia: A Case Report

Catatonia is a psychomotor syndrome first described by Karl Kahlbaum in 1874. The signs and symptoms of catatonia include mutism, posturing, echophenomena, negativism, waxy flexibility, and automatic obedience.1 Malignant catatonia (MC) is a severe variant of catatonia marked by hyperthermia, autonomic instability and rigidity.2 Neuroleptic malignant syndrome (NMS) is a subtype of MC, with a specific etiology. Causes of MC include psychiatric illness, antipsychotic use, corticosteroid intoxication, and illicit drug use.
Source: Psychosomatics - Category: Psychiatry & Psychology Authors: Tags: Case Report Source Type: research