Dual (Anticoagulant Plus Single Antiplatelet) vs Triple (Anticoagulant Plus Dual Antiplatelet) Antithrombotic Therapy – “Real World” Experience

Atrial fibrillation (AF) is a common arrhythmia that increases in prevalence with advancing age and in patients with coronary artery disease, revascularization, particularly with percutaneous coronary intervention (PCI), is also common. Both disease states have thrombosis as a core pathophysiologic process which requires treatment – low sheer stress thrombi in AF and intracoronary high sheer stress thrombi in PCI. For the 10–20% of patients who have both AF and undergo PCI, preventing thrombotic complications will require inhibition of both processes requiring simultaneous use of anticoagulation and antiplatelet therapy.

Source: Progress in Cardiovascular Diseases - January 21, 2018 Category: Cardiology Authors: Mark B. Effron, C. Michael Gibson Source Type: research