Mesenchymal stem cell derived microvesicles alleviate pulmonary arterial hypertension by regulating renin angiotensin system
In recent years, microvesicles derived from mesenchymal stem cells (MSCs) have been proved to be able to improve the outcome of pulmonary arterial hypertension (PAH) in many respects, but the underlying mechanisms of it still remain unclear. Since the renin angiotensin system (RAS) has been found to be closely related to PAH, the present study was designed to investigate whether the effect of MSC-derived microvesicles on PAH was correlated with RAS.
Source: Journal of the American Society of Hypertension - Category: Cardiology Authors: Zhenjun Liu, Jinghu Liu, Mengyuan Xiao, Junxian Wang, Feng Yao, Weikai Zeng, Liqin Yu, Yuejie Guan, Wenyan Wei, Zijian Peng, Kunpeng Zhu, Jin Wang, Zhongyuan Yang, Jixin Zhong, Jianying Chen Tags: Research Article Source Type: research