In-vitro and in-vivo design and validation of an injectable polysaccharide-hydroxyapatite composite material for sinus floor augmentation

Polysaccharide-based composite matrices consisting of natural polysaccharides, pullulan and dextran supplemented with hydroxyapatite (Matrix-HA) have recently been developed. The principal objective of this study was to evaluate the capacities of this composite material to promote new bone formation in a sinus lift model in the sheep. Secondary objectives were to evaluate in vitro properties of the material regarding cell adhesion and proliferation.

Source: Dental Materials - April 7, 2018 Category: Materials Science Authors: J.C. Fricain, R. Aid, S. Lanouar, D.B. Maurel, D. Le Nihouannen, S. Delmond, D. Letourneur, J. Amedee Vilamitjana, S. Catros Source Type: research