Serum lipidomic analysis for the discovery of biomarkers for major depressive disorder in drug-free patients

Recent studies have suggested that changes in blood lipid profile may be related to the pathogenesis of some important neuropsychiatric diseases such as depression, schizophrenia, and Alzheimer's disease (Demirkan et  al., 2013; Kakefuda et al., 2010; Liu et al., 2015; McEvoy et al., 2013; Sato et al., 2012). Lipids constitute approximately half of the dry weight of the brain and are implicated in important brain functions including membrane composition, signal transduction, and biological messenger functio ns, in addition to physiological processes such as energy metabolism and neuroendocrine function (Fonteh et al., 2006).
Source: Psychiatry Research - Category: Psychiatry Authors: Source Type: research