The serotonin transporter 5-HTTLPR polymorphism and the risk for insomnia: a non-replication

In the June 2014 issue of Sleep Medicine, Huang et  al. (2014) reported a genetic association study investigating the effect of 5-HTTLPR on insomnia [1]. In line with previous findings [2], the results demonstrated that the 5-HTTLPR short allele was associated with a higher insomnia risk relative to the long allele. The authors revealed that an int eraction between 5-HTTLPR and stress may further contribute to this relationship, corresponding with earlier findings on subjective sleep quality [3].

Source: Sleep Medicine - March 31, 2018 Category: Sleep Medicine Authors: Jens H. van Dalfsen, C. Rob Markus Tags: Letter to the Editor Source Type: research