PREDICTORS of clinical response in a double-blind placebo controlled crossover trial of gabapentin enacarbil for RESTLESS legs syndrome

Restless Legs Syndrome (RLS) is a sensory-motor disorder which produces sleep disturbance. Using data from a large clinical trial of gabapentin enacarbil (GEn) we sought to assess the ability of baseline, and changes from baseline, in clinical trial endpoints to predict treatment response.

Source: Sleep Medicine - April 25, 2018 Category: Sleep Medicine Authors: John W. Winkelman, Mark J. Jaros Tags: Original Article Source Type: research