Antiviral resistance due to deletion in the neuraminidase gene and defective interfering-like viral polymerase basic 2 RNA of influenza A virus subtype H3N2

Influenza is normally an acute self-limiting disease of a week ’s duration; however, in immunocompromised patients, prolonged infections lasting months have been reported [1–4]. Prevention of severe influenza is mainly based on immunizations with vaccines produced annually to accommodate the antigenically changing seasonal viruses [5,6]. The effect of vacci nation in immunocompromised patients is questionable which is why other modes of prevention and/or treatment are considered for this risk group [7–12].
Source: Journal of Clinical Virology - Category: Virology Authors: Source Type: research