Primary Epstein-Barr virus infection

Epstein-Barr virus (EBV) is arguably the most ubiquitous of human viruses, infecting at least 90% of adults worldwide [1]. It is also the first human cancer virus, having been recognized as the cause of endemic Burkitt lymphoma in the 1960s [2 –4]. In addition to Burkitt lymphoma, EBV is implicated in the pathogenesis of Hodgkin lymphoma [5], nasopharyngeal carcinoma [6,7], gastric cancer [8], and a myriad of malignancies in individuals with inherited or acquired immunodeficiency [9]. EBV is also considered to be a major environmental r isk factor for multiple sclerosis [10].
Source: Journal of Clinical Virology - Category: Virology Authors: Tags: Review Source Type: research