Polyarthropathy and anterior uveitis as paraneoplastic syndromes in a guinea pig with disseminated lymphoma

A 4-year-old intact male guinea pig was presented for evaluation of ocular pain and forelimb lameness. Initial examination confirmed bilateral anterior uveitis and the lameness was attributed to a bilateral carpal and metacarpal polyarthropathy. Carpal joint taps revealed non-septic marked mixed inflammation later confirmed as a non-erosive immune-mediated polyarthropathy (IMPA). Treatment with topical steroid ophthalmic ointment resulted in rapid resolution of the uveitis; the arthropathy was initially managed with pain medication and anti-inflammatories, then later with doxycycline and cyclosporine.
Source: Journal of Exotic Pet Medicine - Category: Veterinary Research Authors: Source Type: research