Mindin deficiency in macrophages protects against foam cell formation and atherosclerosis by targeting LXR-{beta}

Conclusions -The present study demonstrated that mindin deficiency serves as a novel mediator that protects against foam cell formation and atherosclerosis by directly interacting with LXR-β.

Source: Clinical Science - April 25, 2018 Category: Biomedical Science Authors: Zhang, C., Qin, J.-J., Gong, F.-H., Tong, J.-J., Cheng, W.-L., Wang, H., Zhang, Y., Zhu, X., She, Z.-G., Xia, H., Zhu, L.-H. Tags: PublishAheadOfPrint Source Type: research