Effect of multiple low-dose PGF2 α injections on the mature corpus luteum in non-pregnant bitches

This study investigated molecular regulation in the canine corpus luteums/corpora lutea (CL) following multiple low-dose prostaglandin F2 alpha (PGF2 α) injections in non-pregnant bitches around 30–35 days after ovulation. The CL were obtained by ovariohysterectomy 1 h after the last PGF2α injection. The subjects were divided into the following groups: control (no PGF2α injection, n = 4), one PGF2α injection (injection at 0 h, 1PGF, n = 4), two PGF2α injection (injection at 0 and 8 h, 2PGF, n = 4), and three PGF2α injection (injection at 0, 8 and 24 h, 3PGF, n = 4).

Source: Theriogenology - February 4, 2018 Category: Genetics & Stem Cells Authors: Eyyup H. Ucar, Hayrettin Cetin, Mehmet O. Atli Source Type: research