A Candidate Imaging Marker for Early Detection of Charcot Neuroarthropathy
Inflammation-mediated foot osteopenia may play a pivotal role in the etiogenesis, pathogenesis, and therapeutic outcomes in individuals with diabetes mellitus (DM), peripheral neuropathy (PN), and Charcot neuroarthropathy (CN). Our objective was to establish a volumetric quantitative computed tomography –derived foot bone measurement as a candidate prognostic imaging marker to identify individuals with DMPN who were at risk of developing CN. We studied 3 groups: 16 young controls (27 ± 5 years), 20 with DMPN (57 ± 11 years), and 20 with DMPN and CN (55 ± 9 years).
Source: Journal of Clinical Densitometry - Category: Radiology Authors: Paul K. Commean, Kirk E. Smith, Charles F. Hildebolt, Kathryn L. Bohnert, David R. Sinacore, Fred W. Prior Tags: Original Article Source Type: research
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