Trabecular Bone Score and Hip Structural Analysis in Patients With Atypical Femur Fractures

Bisphosphonate use has declined dramatically in recent years, partly because of fear of rare side effects like atypical femur fractures (AFFs). It is therefore desirable to have a diagnostic method to identify those at risk of AFF to prevent this serious complication. We compared trabecular microarchitecture and hip geometry between 30 patients with AFF and 141 controls of similar age and sex, using bisphosphonates. Trabecular bone score (TBS) and hip structural analysis (HSA) were used to assess trabecular microarchitecture and macroscopic hip geometry from dual-energy X-ray absorptiometry images of the lumbar spine and hip, respectively.

Source: Journal of Clinical Densitometry - April 13, 2018 Category: Radiology Authors: Sanne K.C. Buitendijk, Denise M. van de Laarschot, Alexandra A.A. Smits, Fjorda Koromani, Fernando Rivadeneira, Thomas J. Beck, M. Carola Zillikens Tags: Original Article Source Type: research