Cognitive predictors of illness course at 12 months after first-episode of depression

Major Depressive Disorder (MDD) entails cognitive dysfunction in many cognitive domains, but it is still uncertain whether such deficits are present in the early stages. The purpose of the study is to determine the cognitive performance in first episode depression (FED) exploring the presence of different cognitive profiles, and the role of cognition in FED at baseline and long-term. Ninety subjects (18 –50 years) were included, 50 patients with a FED and 40 healthy controls. Participants were assessed with a neuropsychological battery, covering language, attention, verbal memory, processing speed and executive domains.

Source: European Neuropsychopharmacology - February 23, 2018 Category: Psychiatry & Psychology Authors: M. Vicent-Gil, A. Keymer-Gausset, M. Serra-Blasco, M. Carceller-Sindreu, J. de Diego-Adeli ño, J. Trujols, M. Mur, V. Pérez, E. Alvarez, N. Cardoner, M.J. Portella Source Type: research