High expression of synthesis of cytochrome c oxidase 2 and TP53-induced glycolysis and apoptosis regulator can predict poor prognosis in human lung adenocarcinoma

Synthesis of cytochrome c oxidase 2 (SCO2) and TP53-induced glycolysis and apoptosis regulator (TIGAR) are two p53-mediated proteins that can play a regulatory role in cancer energy metabolism. However, no study has examined the association of SCO2 and TIGAR with the prognosis of patients with lung adenocarcinoma (AC). In our study, the expression of SCO2 and TIGAR proteins in lung AC was detected, and the potential relation to prognosis was evaluated, aiming to take a further view of lung AC progression.

Source: Human Pathology - April 7, 2018 Category: Pathology Authors: Jiabin Liu, Funian Lu, Yan Gong, Chen Zhao, Qi Pan, Stephanie Ballantyne, Xianda Zhao, Sufang Tian, Honglei Chen Tags: Original contribution Source Type: research