High salt intake increases plasma trimethylamine N-oxide (TMAO) concentration and produces gut dysbiosis in rats.

• Increased plasma TMAO, a bacteria metabolite, is a cardiovascular risk marker.• We found that high salt intake increases plasma TMAO in rats.• High salt intake altered gut bacteria composition.• High-salt diet may affect an interplay between gut bacteria and host homeostasis.

Source: Nutrition - March 22, 2018 Category: Nutrition Authors: Klaudia Bielinska, Marek Radkowski, Marta Grochowska, Karol Perlejewski, Tomasz Huc, Kinga Jaworska, Daisuke Motooka, Shota Nakamura, Marcin Ufnal Source Type: research