Age Differences by Sex in Antiretroviral-Na ïve Participants: Pooled Analysis from Randomized Clinical Trials

Age and sex effects on antiretroviral therapy (ART) response are not well elucidated. Our pooled analysis of 40 randomized clinical trials measured the association of age and sex on CD4+ T cell count changes and virologic suppression using multivariable regression modeling. The average increase in CD4+ T cell count from baseline to week 48 was 17.3  cells/mm3 lower and clinically insignificant (95% confidence interval −30.8 to −3.8) among women ages ≥ 50 years (n = 573), compared to women ≤ 35 years (n = 3,939).
Source: Journal of the Association of Nurses in AIDS Care - Category: Nursing Authors: Tags: Feature Source Type: research