Activity of a Nitric Oxide Generating Wound Treatment System against Wound Pathogen Biofilms

The microbial burden of acute and chronic wounds plays an important role in impaired healing and development of infection-related complications. Prevalence of infection in chronic wounds is reported as 53 % [1]. In these patients, inadequate infection management can result in lower limb amputation and bloodstream invasion, with complications such as sepsis, multi-organ failure and death [2]. Biofilm formation is now thought to exacerbate wound infection and delay healing, not only in chronic wounds [3, 4] but also following acute injury [5].
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research