High prevalence of multidrug resistant international clones among macrolide resistant Streptococcus pneumoniae strains in immunocompromised Patients in Tunisia

S. pneumoniae is one of the major pathogens responsible for meningitis and for respiratory tract infections, such as otitis and pneumonia. The prevalence of β-lactam resistance and the role of atypical pathogens in community-acquired respiratory tract infections led to the increase of macrolide prescription. However, macrolide resistant isolates increased considerably the last decade with important geographical variations among involved phenotypes and genotypes. This increase is due to antibiotic consumption and/or clonal diffusion of resistant strains [1].
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research