Adverse events of fluoroquinolones vs. other antimicrobials prescribed in primary care: A systematic review and meta-analysis of randomized controlled trials

Fluoroquinolones (FQs) are broad-spectrum antimicrobial agents that are highly effective for the treatment of a variety of infections however, their use as a first-line treatment is limited at least in part due to antimicrobial resistance [1]. FQs are recommended as second-line treatment for urinary tract infections (UTIs) or respiratory tract infections (RTIs) in general practice [2 –5]. FQ are associated with common AEs impacting the gastrointestinal ((GI), such as nausea, vomiting, diarrhoea and abdominal pain and central nervous system (CNS) (headache, dizziness) [6–8].
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Tags: Review Source Type: research