HLA variation and disease

Nature Reviews Immunology 18, 325 (2018). doi:10.1038/nri.2017.143 Authors: Calliope A. Dendrou, Jan Petersen, Jamie Rossjohn & Lars Fugger Fifty years since the first description of an association between HLA and human disease, HLA molecules have proven to be central to physiology, protective immunity and deleterious, disease-causing autoimmune reactivity. Technological advances have enabled pivotal progress in the determination of the molecular mechanisms that underpin
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research