Immunometabolism: Itaconate helps KEAP1's cool

Nature Reviews Immunology 18, 294 (2018). doi:10.1038/nri.2018.27 Author: Grant Otto Itaconate alkylates KEAP1 to regulate NRF2 activity and induce an anti-inflammatory response in macrophages
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Research Highlight Source Type: research