Plasma homocysteine in first-episode schizophrenia: 1-year outcome, a prospective study

Conclusion We found higher rates of Hcy in patients with first-episode schizophrenia compared with matched controls. Our results suggest that Hcy might play a role in the pathogenesis of schizophrenia and may negatively influence outcome in terms of symptom severity and treatment characteristics; future studies are required to examine this association further. In the meantime, there is a need for more widespread testing of Hcy levels in first-episode schizophrenia and for the development of appropriate management strategies.
Source: Middle East Current Psychiatry - Category: Psychiatry Tags: Original Articles Source Type: research