Does nonmetastatic castration-resistant prostate cancer still exist?

Does nonmetastatic castration-resistant prostate cancer still exist?Does nonmetastatic castration-resistant prostate cancer still exist?, Published online: 23 April 2018; doi:10.1038/s41571-018-0025-zAfter almost 20 years of negative trials of novel therapies for patients with nonmetastatic castration-resistant prostate cancer (nmCRPC), two androgen receptor antagonists have shown favourable outcomes in phase III trials involving patients with high-risk nmCRPC. Herein, the history of nmCRPC and clinical trials in this disease setting are discussed and a perspective on molecular imaging and clinical management of nmCRPC is offered.
Source: Nature Clinical Practice Oncology - Category: Cancer & Oncology Authors: Source Type: research