Pancreatic cancer: The COMPASS shows the way
Nature Reviews Cancer 18, 373 (2018).
doi:10.1038/nrc.2018.29
Author: Sarah Seton-Rogers
Deregulation of the COMPASS-like complex, via loss of KDM6A in females and loss of both KDM6A and its Y chromosome homologue UTY in males, is important for activation of oncogene-associated super-enhancers and the development of pancreatic adenocarcinoma of the squamous subtype.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Sarah Seton-Rogers Tags: Research Highlight Source Type: research