Breast cancer: Obesity — tipping the scales of resistance

Nature Reviews Cancer 18, 265 (2018). doi:10.1038/nrc.2018.31 Author: Conor A. Bradley Using clinical tissue specimens and mouse models of breast cancer, Incio et al. show that obesity promotes the upregulation of interleukin-6 and fibroblast growth factor 2 in the tumour microenvironment, which confer resistance to anti-vascular endothelial growth factor therapy.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research