Loss of ARID1A expression is associated with poor prognosis in patients with gastric cancer

This study observed and analyzed ARID1A expression and its correlation with prognosis in gastric carcinoma. Postoperative sections of 98 patients with primary gastric cancer and 40 patients with gastric benign lesions were examined by immunohistochemistry. ARID1A deficiency was observed in 19.39% of gastric cancer tissues, 4.08% of matched paracancerous tissues, and 2.5% of normal gastric mucosa.

Source: Human Pathology - April 21, 2018 Category: Pathology Authors: Yi Ping Zhu, Li Li Sheng, Jing Wu, Mo Yang, Xian Feng Cheng, Ning Ni Wu, Xiao Bing Ye, Juan Cai, Lu Wang, Qian Shen, Jian Qiu Wu Source Type: research