Comparison of 4 commercially available group B Streptococcus molecular assays using remnant rectal –vaginal enrichment broths

The incidence of neonatal Group B streptococcal (GBS) disease has significantly declined since the widespread implementation of prenatal screening of expectant mothers for urogenital and gastrointestinal tract GBS colonization. Screening methods have evolved from exclusively culture-based approaches to more rapid and highly sensitive molecular methods. We chose to evaluate the performance of 4 commercially available GBS molecular tests for detection of GBS colonization using 299 antepartum rectal –vaginal specimens submitted to our laboratory for routine GBS screening.
Source: Diagnostic Microbiology and Infectious Disease - Category: Microbiology Authors: Source Type: research