Effects of Sucralose on Insulin and GLP-1 Secretion in Healthy Subjects: A Randomized Double-Blind, Placebo Controlled Trial

• Four-week consumption of sucralose decreased insulin sensitivities in healthy volunteers.• Acute insulin response was also reduced after sucralose consumption.• Glucose-stimulated GLP-1 secretion was enhanced after chronic sucralose exposure.• Sucralose is not metabolically inactive, but a ffects insulin and GLP-1 responses

Source: Nutrition - April 20, 2018 Category: Nutrition Authors: Amornpan Lertrit, Sasinee Srimachai, Sunee Saetung, Suwannee Chanprasertyothin, La-or Chailurkit, Chatvara Areevut, Pornalat Katekao, Boonsong Ongphiphadhanakul, Chutintorn Sriphrapradang Source Type: research