[Correspondence] Colistin versus colistin plus meropenem for severe infections Authors' reply

We appreciate Daniele Giacobbe's Correspondence regarding the importance of colistin minimum inhibitory concentrations. A study showed that both gradient-based and semi-automated devices can overestimate susceptibility to colistin.1 In our trial,2 we recruited patients who were infected with colistin-susceptible (carbapenem non-susceptible) Gram-negative bacteria on the basis of several tests —including the Etest (BioMérieux, Marcy-l'Étoile, France), Vitek-2 (BioMérieux), and BD Phoenix (BD Diagnostics, Sparks, NV, USA) for colistin susceptibilities—done in the clinical laboratories of participating centres.
Source: The Lancet Infectious Diseases - Category: Infectious Diseases Authors: Tags: Correspondence Source Type: research