Systemic Therapy of Atopic Dermatitis: Welcome to the Revolution.

Systemic Therapy of Atopic Dermatitis: Welcome to the Revolution. Semin Cutan Med Surg. 2016 Mar;35(3):S103-S105 Authors: Eichenfield LF, Stein Gold LF Abstract Until recently, systemic therapy of atopic dermatitis was limited to off-label use of immunomodulators, which can pose significant safety concerns, and treatment with systemic corticosteroids, not recommended in the most recent guidelines. The introduction of dupilumab in 2017 marked a major advance in systemic therapy for atopic dermatitis. It has demonstrated long-term efficacy in adults with moderate to severe disease, and is being studied in children. Several other biologic agents and "small molecules" with varying mechanisms of action are in phase 2 or 3 development. Semin Cutan Med Surg 36(supp4):S103-S105. PMID: 29659645 [PubMed]
Source: Seminars in Cutaneous Medicine and Surgery - Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research