microRNAs in Sudden Unexpected Death in Epilepsy (SUDEP): location matters.

We read with great enthusiasm the article published by De Matteis et al. who have elegantly demonstrated a significant up-regulation of microRNAs (miRNAs) expression profiling (miR-301a-3p) in both the plasma and the hippocampus in a case of SUDEP due to drug-resistant mesial temporal lobe epilepsy [1]. With these results, the authors supported the idea that miRNAs as an innovative class of biomarkers compatible with an adequate analysis of biospecimens obtained from forensic autopsies [1]. Given the dearth of published data about the relationship of miRNA in SUDEP occurrence, we applaud Dr.
Source: Legal Medicine - Category: Forensic Medicine Authors: Tags: Letter to Editor Source Type: research