Antifungal activity of cinnamaldehyde against candida albicans.
In this study, cinnamaldehyde possessed antifungal
activity against C. albicans with a minimum inhibitory concentration of 125 μg/ml.
At sub-inhibitory concentrations, cinnamaldehyde significantly reduced germ tube
formation, proteinase and phospholipase activities in a dose dependent manner
(p<0.01). Cinnamaldehyde also significantly inhibited the adhesion of C. albicans to
buccal epithelial cells (p<0.01). In our study, cinnamaldehyde had in vitro activity
against C. albicans and inhibited some of its virulence factors.
PMID: 29644831 [PubMed - in process]
Source: Southeast Asian Journal of Tropical Medicine and Public Health - Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research