Antifungal activity of cinnamaldehyde against candida albicans.

In this study, cinnamaldehyde possessed antifungal activity against C. albicans with a minimum inhibitory concentration of 125 μg/ml. At sub-inhibitory concentrations, cinnamaldehyde significantly reduced germ tube formation, proteinase and phospholipase activities in a dose dependent manner (p<0.01). Cinnamaldehyde also significantly inhibited the adhesion of C. albicans to buccal epithelial cells (p<0.01). In our study, cinnamaldehyde had in vitro activity against C. albicans and inhibited some of its virulence factors. PMID: 29644831 [PubMed - in process]
Source: Southeast Asian Journal of Tropical Medicine and Public Health - Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research